How to ask Node

Node 2.0 is the point-of-care mode of Cynaps Chat. It gives short bedside answers from the guidelines, drug information and textbooks in the Cynaps library, and every line it writes points to its source. It is open to verified doctors on the web; the Android and iOS apps are coming soon.

What Node is for

Quick, specific questions at the bedside or in the OPD: a dose, a first-line choice, a threshold, a criterion, the first steps in an emergency.
Answers are short on purpose: a few lines, each with a source you can open.
Our library includes Indian national guidance (for example ICMR and MoHFW documents) alongside international guidelines.

Questions that work well

Be specific. Name the drug or condition, and give the patient factors that change the answer.

Ask like thisWhy it works

A dose with patient factors: age, weight, kidney or liver function, pregnancyWhy it worksNode can pick the right dose band and say which source it comes from

Name the guideline you want ("as per ICMR …")Why it worksNode searches the whole library; naming the guideline helps it find the right passage

A threshold or criterion (when to admit, when to refer, a cut-off)Why it worksThese are stated plainly in guidelines, so the answer is exact and cited

First-line treatment for a named condition and setting (OPD or ward)Why it worksNode gives the first-line choice first, labelled by setting

A children's dose with weightWhy it worksPaediatric doses depend on weight; giving it avoids a vague range

Two drugs together ("Can I give X with Y?")Why it worksOne drug pair is answered as an interaction

What a good answer looks like

Each line shows its source pill; open it to read the passage it comes from.

Real examples, shown for illustration. These answers were written by Node 2.0 and trimmed for length. They are not clinical advice and are not a substitute for your own judgement or your hospital's protocol. Answers can change as the library and Node improve. Always open the source and check the dose or decision against it before you act. The questions are examples, not real patients.

Maximum daily dose of metformin in an adult with eGFR 35?

For eGFR 35, the maximum daily metformin dose is 1,000 mg. KDIGO
Monitor renal function every 3 months. RSSDI
Stop metformin if eGFR falls below 30 mL/min/1.73 m². KDIGO

Ondansetron dose for vomiting in pregnancy?

Ondansetron: 4 mg orally or IV for severe nausea/vomiting in pregnancy; avoid in the first trimester. FOGSI
Use is generally reserved for refractory cases. FOGSI
Avoid IV doses >16 mg/day; consider electrolyte and ECG monitoring with arrhythmia risk factors. FOGSI

As per NTEP, daily isoniazid dose for TB preventive treatment in adults?

NTEP: isoniazid 5 mg/kg/day for adults aged 10 years and older, with a maximum of 300 mg/day. NTEP (MoHFW)

As per ICMR, first-line treatment for uncomplicated P. vivax malaria in adults?

ICMR: chloroquine 25 mg/kg over 3 days, plus primaquine 0.25 mg/kg daily for 14 days. ICMR
Primaquine is contraindicated in pregnancy, infants and people with G6PD deficiency. MoHFW (GoI)

Haemoglobin cut-off for anaemia in pregnancy?

Anaemia is defined as haemoglobin <11 g/dL in the first and third trimesters and <10.5 g/dL in the second trimester. FOGSI

At what CURB-65 score should an adult with pneumonia be admitted?

Admit at CURB-65 score 2 or more; current NICE guidance allows alternatives to inpatient care at score 2, while recommending inpatient or critical care at 3 or more. WHO

First-line antibiotic for uncomplicated cystitis in a non-pregnant woman?

Nitrofurantoin 100 mg q12h for 5 days is a first-line choice for uncomplicated cystitis. NCDC (GoI)
Fosfomycin 3 gm single dose is another first-line option. AIIMS Rishikesh
Avoid nitrofurantoin if pyelonephritis or systemic infection is suspected. ICMR

Can clarithromycin be given with simvastatin?

No—clarithromycin and simvastatin are contraindicated together because of increased risk of myopathy, including rhabdomyolysis. FDA
If clarithromycin is necessary, suspend simvastatin for the duration of clarithromycin treatment. FDA

Questions to avoid, and what to ask instead

AvoidAsk instead

Patient names, phone numbers, ID numbers or addresses — never type theseAsk insteadDescribe the patient: "a 62-year-old man with eGFR 35"

A long case summary with many problems at onceAsk insteadOne clear question at a time. Longer case reviews are for Sage (Consult), coming soon

A literature review or "what does the research say"Ask insteadVeda (Research), coming soon

Non-clinical questionsAsk insteadNode answers clinical questions only

An interaction or regimen question across three or more drugsAsk insteadAsk about each drug, or each pair, separately. (Doses for several named drugs are fine: "Doses of amlodipine, losartan and atorvastatin for an adult?")

Two questions in one message, or several test values at onceAsk insteadOne question, or one test value, at a time

"Explain…" or "compare…"Ask insteadAsk for the one fact you need: a dose, a threshold, a schedule or a first-line choice

A whole case or a management planAsk insteadAsk for the one fact you need, e.g. a dose or a threshold

A child's question without an age or weightAsk insteadGive the age or weight, or say "in an adult", so the answer keeps to one group

Node is not a substitute for your clinical judgement. Check doses and decisions against the cited source.

Reading the sources

Each line ends with a source pill: the main issuer, and "+N" when more sources support it.
Tap or hover the pill to see the exact passage Node used, then "Open source ↗" to read it in full.
If a source looks wrong or does not support the line, tell us with the thumbs-down on the answer or write to support@cynaps.co.

Emergencies

If your question describes a live emergency, Node shows a short safety line first:

This may be an emergency. Start your emergency protocol now — check airway, breathing and circulation, and start CPR if the patient is not breathing normally — and call for help. Outside a hospital, call 108 or 112, continue CPR until the ambulance arrives, and arrange transfer.

It then gives first bedside steps only, each with its source, or says it cannot if the library has nothing usable. Node does not yet recognise every emergency described only by its signs: always follow your own emergency protocol first.

Privacy

Never type patient identifiers. Before a typed question is sent to an AI provider, Cynaps removes direct identifiers such as phone numbers and ID numbers; this is not perfect.
What we store and who processes it: see our Privacy Policy.

Questions doctors ask

Why did Node not answer my question?

Node answers one focused question at a time. When a question asks for several things, an explanation or a whole case, Node says so in one line and suggests how to ask instead. If the library has nothing on a topic, it says that too.

Why is the answer so short?

Node is built for the bedside: the key line first, each with its source.

Which sources does Node use?

Indian and international clinical guidelines, drug information and standard textbooks in the Cynaps library. Every line names its source.

How do I give feedback?

Rate the answer with the thumbs below it, or write to support@cynaps.co.